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Accurate and efficient detection of gene fusions from RNA sequencing data

The identification of gene fusions from RNA sequencing data is a routine task in cancer research and precision oncology. However, despite the availability of many computational tools, fusion detection remains challenging. Existing methods suffer from poor prediction accuracy and are computationally...

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Detalles Bibliográficos
Autores principales: Uhrig, Sebastian, Ellermann, Julia, Walther, Tatjana, Burkhardt, Pauline, Fröhlich, Martina, Hutter, Barbara, Toprak, Umut H., Neumann, Olaf, Stenzinger, Albrecht, Scholl, Claudia, Fröhling, Stefan, Brors, Benedikt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919457/
https://www.ncbi.nlm.nih.gov/pubmed/33441414
http://dx.doi.org/10.1101/gr.257246.119