Lipotoxic Impairment of Mitochondrial Function in β-Cells: A Review

Lipotoxicity is a major contributor to type 2 diabetes mainly promoting mitochondrial dysfunction. Lipotoxic stress is mediated by elevated levels of free fatty acids through various mechanisms and pathways. Impaired peroxisome proliferator-activated receptor (PPAR) signaling, enhanced oxidative str...

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Detalles Bibliográficos
Autores principales: Römer, Axel, Linn, Thomas, Petry, Sebastian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919463/
https://www.ncbi.nlm.nih.gov/pubmed/33672062
http://dx.doi.org/10.3390/antiox10020293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919463/
https://www.ncbi.nlm.nih.gov/pubmed/33672062
http://dx.doi.org/10.3390/antiox10020293

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