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Implementing Precision Medicine in Human Frailty through Epigenetic Biomarkers

The main epigenetic features in aging are: reduced bulk levels of core histones, altered pattern of histone post-translational modifications, changes in the pattern of DNA methylation, replacement of canonical histones with histone variants, and altered expression of non-coding RNA. The identificati...

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Detalles Bibliográficos
Autores principales: García-Giménez, José Luis, Mena-Molla, Salvador, Tarazona-Santabalbina, Francisco José, Viña, Jose, Gomez-Cabrera, Mari Carmen, Pallardó, Federico V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919465/
https://www.ncbi.nlm.nih.gov/pubmed/33672064
http://dx.doi.org/10.3390/ijerph18041883