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Aldehyde Dehydrogenase, a Therapeutic Target in Chordoma: Analysis in 3D Cellular Models

Chordomas are rare, slow-growing tumors of the axial skeleton. These tumors are locally aggressive and refractory to conventional therapies. Radical surgery and radiation remain the first-line treatments. Despite these aggressive treatments, chordomas often recur and second-line treatment options ar...

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Detalles Bibliográficos
Autores principales: Locquet, Marie-Anaïs, Dechaume, Anne-Lise, Berchard, Paul, Abbes, Lhorra, Pissaloux, Daniel, Tirode, Franck, Ramos, Inès, Bedoucha, Julie, Valantin, Julie, Karanian, Marie, Perret, Raul, Gille, Olivier, Blay, Jean-Yves, Dutour, Aurélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919493/
https://www.ncbi.nlm.nih.gov/pubmed/33672032
http://dx.doi.org/10.3390/cells10020399