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The study of antiviral drugs targeting SARS-CoV-2 nucleocapsid and spike proteins through large-scale compound repurposing

Contributing to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) clinical treatment, a drug library encompassing approximately 3,142 clinical-stage or FDA-approved small molecules is profiled to identify the candidate therapeutic inhibitors targeting nucleocapsid protein (N) and spike pr...

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Detalles Bibliográficos
Autores principales: Hu, Xuqiao, Zhou, Zhenru, Li, Fei, Xiao, Yang, Wang, Zhaoyang, Xu, Jinfeng, Dong, Fajin, Zheng, Hairong, Yu, Rongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919521/
https://www.ncbi.nlm.nih.gov/pubmed/33688584
http://dx.doi.org/10.1016/j.heliyon.2021.e06387