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Common Treatment, Common Variant: Evolutionary Prediction of Functional Pharmacogenomic Variants

Pharmacogenomics holds the promise of personalized drug efficacy optimization and drug toxicity minimization. Much of the research conducted to date, however, suffers from an ascertainment bias towards European participants. Here, we leverage publicly available, whole genome sequencing data collecte...

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Detalles Bibliográficos
Autores principales: Scheinfeldt, Laura B., Brangan, Andrew, Kusic, Dara M., Kumar, Sudhir, Gharani, Neda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919641/
https://www.ncbi.nlm.nih.gov/pubmed/33669176
http://dx.doi.org/10.3390/jpm11020131