Cargando…
Common Treatment, Common Variant: Evolutionary Prediction of Functional Pharmacogenomic Variants
Pharmacogenomics holds the promise of personalized drug efficacy optimization and drug toxicity minimization. Much of the research conducted to date, however, suffers from an ascertainment bias towards European participants. Here, we leverage publicly available, whole genome sequencing data collecte...
Autores principales: | Scheinfeldt, Laura B., Brangan, Andrew, Kusic, Dara M., Kumar, Sudhir, Gharani, Neda |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919641/ https://www.ncbi.nlm.nih.gov/pubmed/33669176 http://dx.doi.org/10.3390/jpm11020131 |
Ejemplares similares
-
Common Genetic Risk for Melanoma Encourages Preventive Behavior Change
por: Diseati, Lori, et al.
Publicado: (2015) -
Pharmacogenomics: From Basic Research to Clinical Implementation
por: Scheinfeldt, Laura B.
Publicado: (2021) -
Emerging trends in pharmacogenomics: from common variant associations toward comprehensive genomic profiling
por: Ingelman-Sundberg, Magnus, et al.
Publicado: (2023) -
Do rare variant genotypes predict common variant genotypes?
por: Kent, Jack W, et al.
Publicado: (2011) -
The Evolutionary History of Common Genetic Variants Influencing Human Cortical Surface Area
por: Tilot, Amanda K, et al.
Publicado: (2020)