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Phosphodianion Activation of Enzymes for Catalysis of Central Metabolic Reactions
[Image: see text] The activation barriers ΔG(⧧) for k(cat)/K(m) for the reactions of whole substrates catalyzed by 6-phosphogluconate dehydrogenase, glucose 6-phosphate dehydrogenase, and glucose 6-phosphate isomerase are reduced by 11–13 kcal/mol by interactions between the protein and the substrat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919737/ https://www.ncbi.nlm.nih.gov/pubmed/33560827 http://dx.doi.org/10.1021/jacs.0c13423 |