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OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase

Aurora kinases are serine/threonine kinases required for cell proliferation and are overexpressed in many human cancers. Targeting Aurora kinases has been a therapeutic strategy in cancer treatment. Here, we attempted to identify a deubiquitinase (DUB) that regulates Aurora kinase A (Aurora-A) prote...

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Detalles Bibliográficos
Autores principales: Kim, Hyo Jin, Kim, Jongchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919836/
https://www.ncbi.nlm.nih.gov/pubmed/33669244
http://dx.doi.org/10.3390/ijms22041936