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Novel Tocolytic Strategy: Modulating Cx43 Activity by S-Nitrosation

Currently available tocolytics are ineffective at significantly delaying preterm birth. This is due in part to our failure to better understand the mechanisms that drive spontaneous preterm labor (sPTL). Cyclic nucleotides are not the primary contributors to myometrial quiescence, but instead nitric...

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Detalles Bibliográficos
Autores principales: Barnett, Scott D., Asif, Hazik, Anderson, Mitchell, Buxton, Iain L. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919864/
https://www.ncbi.nlm.nih.gov/pubmed/33384302
http://dx.doi.org/10.1124/jpet.120.000427