Andrographolide emeliorates maltol aluminium-induced neurotoxicity via regulating p62-mediated Keap1-Nrf2 pathways in PC12 cells

CONTEXT: Andrographolide (Andro) has a neuroprotective effect and a potential for treating Alzheimer’s disease (AD), but the mechanism has not been elucidated. OBJECTIVE: The efficacy of Andro on p62-mediated Kelch-like ECH-associated protein 1(Keap1)-Nuclear factor E2 related factor 2 (Nrf2) pathwa...

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Detalles Bibliográficos
Autores principales: Lu, Jiaqi, Gu, Lili, Li, Qin, Wu, Ningzi, Li, Hongxing, Zhang, Xinyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919883/
https://www.ncbi.nlm.nih.gov/pubmed/33632062
http://dx.doi.org/10.1080/13880209.2021.1883678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919883/
https://www.ncbi.nlm.nih.gov/pubmed/33632062
http://dx.doi.org/10.1080/13880209.2021.1883678

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