Polyamine Analog Diethylnorspermidine Restricts Coxsackievirus B3 and Is Overcome by 2A Protease Mutation In Vitro

Enteroviruses, including Coxsackievirus B3 (CVB3), are pervasive pathogens that cause significant disease, including cardiomyopathies. Unfortunately, no treatments or vaccines are available for infected individuals. We identified the host polyamine pathway as a potential drug target, as inhibiting p...

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Detalles Bibliográficos
Autores principales: Hulsebosch, Bridget M., Mounce, Bryan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920041/
https://www.ncbi.nlm.nih.gov/pubmed/33669273
http://dx.doi.org/10.3390/v13020310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920041/
https://www.ncbi.nlm.nih.gov/pubmed/33669273
http://dx.doi.org/10.3390/v13020310

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