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Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases
The use of inorganic nanoparticles (NPs) has expanded into various industries including food manufacturing, agriculture, cosmetics, and construction. This has allowed NPs access to the human gastrointestinal tract, yet little is known about how they may impact human health. As the gut microbiome con...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920074/ https://www.ncbi.nlm.nih.gov/pubmed/33669290 http://dx.doi.org/10.3390/ijms22041942 |
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author | Ghebretatios, Merry Schaly, Sabrina Prakash, Satya |
author_facet | Ghebretatios, Merry Schaly, Sabrina Prakash, Satya |
author_sort | Ghebretatios, Merry |
collection | PubMed |
description | The use of inorganic nanoparticles (NPs) has expanded into various industries including food manufacturing, agriculture, cosmetics, and construction. This has allowed NPs access to the human gastrointestinal tract, yet little is known about how they may impact human health. As the gut microbiome continues to be increasingly implicated in various diseases of unknown etiology, researchers have begun studying the potentially toxic effects of these NPs on the gut microbiome. Unfortunately, conflicting results have limited researcher’s ability to evaluate the true impact of NPs on the gut microbiome in relation to health. This review focuses on the impact of five inorganic NPs (silver, iron oxide, zinc oxide, titanium dioxide, and silicon dioxide) on the gut microbiome and gastrointestinal tract with consideration for various methodological differences within the literature. This is important as NP-induced changes to the gut could lead to various gut-related diseases. These include irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), celiac disease, and colorectal cancer. Research in this area is necessary as the use of NPs in various industries continues to grow along with the number of people suffering from chronic gastrointestinal diseases. |
format | Online Article Text |
id | pubmed-7920074 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79200742021-03-02 Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases Ghebretatios, Merry Schaly, Sabrina Prakash, Satya Int J Mol Sci Review The use of inorganic nanoparticles (NPs) has expanded into various industries including food manufacturing, agriculture, cosmetics, and construction. This has allowed NPs access to the human gastrointestinal tract, yet little is known about how they may impact human health. As the gut microbiome continues to be increasingly implicated in various diseases of unknown etiology, researchers have begun studying the potentially toxic effects of these NPs on the gut microbiome. Unfortunately, conflicting results have limited researcher’s ability to evaluate the true impact of NPs on the gut microbiome in relation to health. This review focuses on the impact of five inorganic NPs (silver, iron oxide, zinc oxide, titanium dioxide, and silicon dioxide) on the gut microbiome and gastrointestinal tract with consideration for various methodological differences within the literature. This is important as NP-induced changes to the gut could lead to various gut-related diseases. These include irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), celiac disease, and colorectal cancer. Research in this area is necessary as the use of NPs in various industries continues to grow along with the number of people suffering from chronic gastrointestinal diseases. MDPI 2021-02-16 /pmc/articles/PMC7920074/ /pubmed/33669290 http://dx.doi.org/10.3390/ijms22041942 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Ghebretatios, Merry Schaly, Sabrina Prakash, Satya Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases |
title | Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases |
title_full | Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases |
title_fullStr | Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases |
title_full_unstemmed | Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases |
title_short | Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases |
title_sort | nanoparticles in the food industry and their impact on human gut microbiome and diseases |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920074/ https://www.ncbi.nlm.nih.gov/pubmed/33669290 http://dx.doi.org/10.3390/ijms22041942 |
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