Cargando…

Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases

The use of inorganic nanoparticles (NPs) has expanded into various industries including food manufacturing, agriculture, cosmetics, and construction. This has allowed NPs access to the human gastrointestinal tract, yet little is known about how they may impact human health. As the gut microbiome con...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghebretatios, Merry, Schaly, Sabrina, Prakash, Satya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920074/
https://www.ncbi.nlm.nih.gov/pubmed/33669290
http://dx.doi.org/10.3390/ijms22041942
_version_ 1783658225991680000
author Ghebretatios, Merry
Schaly, Sabrina
Prakash, Satya
author_facet Ghebretatios, Merry
Schaly, Sabrina
Prakash, Satya
author_sort Ghebretatios, Merry
collection PubMed
description The use of inorganic nanoparticles (NPs) has expanded into various industries including food manufacturing, agriculture, cosmetics, and construction. This has allowed NPs access to the human gastrointestinal tract, yet little is known about how they may impact human health. As the gut microbiome continues to be increasingly implicated in various diseases of unknown etiology, researchers have begun studying the potentially toxic effects of these NPs on the gut microbiome. Unfortunately, conflicting results have limited researcher’s ability to evaluate the true impact of NPs on the gut microbiome in relation to health. This review focuses on the impact of five inorganic NPs (silver, iron oxide, zinc oxide, titanium dioxide, and silicon dioxide) on the gut microbiome and gastrointestinal tract with consideration for various methodological differences within the literature. This is important as NP-induced changes to the gut could lead to various gut-related diseases. These include irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), celiac disease, and colorectal cancer. Research in this area is necessary as the use of NPs in various industries continues to grow along with the number of people suffering from chronic gastrointestinal diseases.
format Online
Article
Text
id pubmed-7920074
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-79200742021-03-02 Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases Ghebretatios, Merry Schaly, Sabrina Prakash, Satya Int J Mol Sci Review The use of inorganic nanoparticles (NPs) has expanded into various industries including food manufacturing, agriculture, cosmetics, and construction. This has allowed NPs access to the human gastrointestinal tract, yet little is known about how they may impact human health. As the gut microbiome continues to be increasingly implicated in various diseases of unknown etiology, researchers have begun studying the potentially toxic effects of these NPs on the gut microbiome. Unfortunately, conflicting results have limited researcher’s ability to evaluate the true impact of NPs on the gut microbiome in relation to health. This review focuses on the impact of five inorganic NPs (silver, iron oxide, zinc oxide, titanium dioxide, and silicon dioxide) on the gut microbiome and gastrointestinal tract with consideration for various methodological differences within the literature. This is important as NP-induced changes to the gut could lead to various gut-related diseases. These include irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), celiac disease, and colorectal cancer. Research in this area is necessary as the use of NPs in various industries continues to grow along with the number of people suffering from chronic gastrointestinal diseases. MDPI 2021-02-16 /pmc/articles/PMC7920074/ /pubmed/33669290 http://dx.doi.org/10.3390/ijms22041942 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ghebretatios, Merry
Schaly, Sabrina
Prakash, Satya
Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases
title Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases
title_full Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases
title_fullStr Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases
title_full_unstemmed Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases
title_short Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases
title_sort nanoparticles in the food industry and their impact on human gut microbiome and diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920074/
https://www.ncbi.nlm.nih.gov/pubmed/33669290
http://dx.doi.org/10.3390/ijms22041942
work_keys_str_mv AT ghebretatiosmerry nanoparticlesinthefoodindustryandtheirimpactonhumangutmicrobiomeanddiseases
AT schalysabrina nanoparticlesinthefoodindustryandtheirimpactonhumangutmicrobiomeanddiseases
AT prakashsatya nanoparticlesinthefoodindustryandtheirimpactonhumangutmicrobiomeanddiseases