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Dysfunctional Inflammation in Cystic Fibrosis Airways: From Mechanisms to Novel Therapeutic Approaches

Cystic fibrosis (CF) is an inherited disorder caused by mutations in the gene encoding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein, an ATP-gated chloride channel expressed on the apical surface of airway epithelial cells. CFTR absence/dysfunction results in defective i...

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Detalles Bibliográficos
Autores principales: Ghigo, Alessandra, Prono, Giulia, Riccardi, Elisa, De Rose, Virginia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920244/
https://www.ncbi.nlm.nih.gov/pubmed/33669352
http://dx.doi.org/10.3390/ijms22041952