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Marek’s disease virus U(S)3 protein kinase phosphorylates chicken HDAC 1 and 2 and regulates viral replication and pathogenesis
Marek’s disease virus (MDV) is a potent oncogenic alphaherpesvirus that elicits a rapid onset of malignant T-cell lymphomas in chickens. Three MDV types, including GaHV-2 (MDV-1), GaHV-3 (MDV-2) and MeHV-1 (HVT), have been identified and all encode a U(S)3 protein kinase. MDV-1 U(S)3 is important fo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920345/ https://www.ncbi.nlm.nih.gov/pubmed/33596269 http://dx.doi.org/10.1371/journal.ppat.1009307 |