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A regularized functional regression model enabling transcriptome-wide dosage-dependent association study of cancer drug response
Cancer treatments can be highly toxic and frequently only a subset of the patient population will benefit from a given treatment. Tumour genetic makeup plays an important role in cancer drug sensitivity. We suspect that gene expression markers could be used as a decision aid for treatment selection...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920352/ https://www.ncbi.nlm.nih.gov/pubmed/33493149 http://dx.doi.org/10.1371/journal.pcbi.1008066 |