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Ym155 Induces Oxidative Stress-Mediated DNA Damage and Cell Cycle Arrest, and Causes Programmed Cell Death in Anaplastic Thyroid Cancer Cells

Anaplastic thyroid cancer (ATC) is one of the most lethal malignancies with a median survival time of about 4 months. Currently, there is no effective treatment, and the development of new therapies is an important and urgent issue for ATC patients. YM155 is a small molecule that was identified as t...

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Detalles Bibliográficos
Autores principales: Xu, Qinqin, Mackay, Ryan P., Xiao, Adam Y., Copland, John A., Weinberger, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920419/
https://www.ncbi.nlm.nih.gov/pubmed/33669447
http://dx.doi.org/10.3390/ijms22041961