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cAMP at Perinuclear mAKAPα Signalosomes Is Regulated by Local Ca(2+) Signaling in Primary Hippocampal Neurons

The second messenger cyclic adenosine monophosphate (cAMP) is important for the regulation of neuronal structure and function, including neurite extension. A perinuclear cAMP compartment organized by the scaffold protein muscle A-kinase anchoring protein α (mAKAPα/AKAP6α) is sufficient and necessary...

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Detalles Bibliográficos
Autores principales: Boczek, Tomasz, Yu, Qian, Zhu, Ying, Dodge-Kafka, Kimberly L., Goldberg, Jeffrey L., Kapiloff, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920539/
https://www.ncbi.nlm.nih.gov/pubmed/33495246
http://dx.doi.org/10.1523/ENEURO.0298-20.2021