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Crm1-Dependent Nuclear Export of Bach1 is Involved in the Protective Effect of Hyperoside on Oxidative Damage in Hepatocytes and CCl(4)-induced Acute Liver Injury

BACKGROUND: Nrf2-Bach1 antioxidant signaling pathway is considered as one of the most important mechanisms of cellular resistance to oxidative injury. The effect of hyperoside (Hyp) on the expression and distribution of Bach1, the relationship of Hyp’s antioxidative effect and the influence of Bach1...

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Detalles Bibliográficos
Autores principales: Cai, Yongqing, Li, Bin, Peng, Dan, Wang, Xianfeng, Li, Pan, Huang, Mingchun, Xing, Haiyan, Chen, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920627/
https://www.ncbi.nlm.nih.gov/pubmed/33658828
http://dx.doi.org/10.2147/JIR.S279249