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Crm1-Dependent Nuclear Export of Bach1 is Involved in the Protective Effect of Hyperoside on Oxidative Damage in Hepatocytes and CCl(4)-induced Acute Liver Injury
BACKGROUND: Nrf2-Bach1 antioxidant signaling pathway is considered as one of the most important mechanisms of cellular resistance to oxidative injury. The effect of hyperoside (Hyp) on the expression and distribution of Bach1, the relationship of Hyp’s antioxidative effect and the influence of Bach1...
Autores principales: | Cai, Yongqing, Li, Bin, Peng, Dan, Wang, Xianfeng, Li, Pan, Huang, Mingchun, Xing, Haiyan, Chen, Jianhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920627/ https://www.ncbi.nlm.nih.gov/pubmed/33658828 http://dx.doi.org/10.2147/JIR.S279249 |
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