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IL-13 Augments Histone Demethylase JMJD2B/KDM4B Expression Levels, Activity, and Nuclear Translocation in Airway Fibroblasts in Asthma

PURPOSE: Asthma is one of the most common obstructive pulmonary diseases worldwide. Epigenetic alterations, including DNA methylation and histone modifications, have been reported to contribute to asthma pathogenesis. Since the inflammation mediator and remodeling trigger, IL-13, is known to play a...

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Detalles Bibliográficos
Autores principales: Bajbouj, Khuloud, Hachim, Mahmood Y., Ramakrishnan, Rakhee K., Fazel, Huwaida, Mustafa, Jumana, Alzaghari, Shahed, Eladl, Mahmoud, Shafarin, Jasmin, Olivenstein, Ronald, Hamid, Qutayba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920726/
https://www.ncbi.nlm.nih.gov/pubmed/33688506
http://dx.doi.org/10.1155/2021/6629844