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Exosomal LINC00174 derived from vascular endothelial cells attenuates myocardial I/R injury via p53-mediated autophagy and apoptosis

In this study, we aim to investigate the regulation of specific long non-coding RNAs (lncRNAs) on the progression of ischemia/reperfusion (I/R) injury. We identified and characterized the exosomes derived from mouse primary aortic endothelial cells. Subsequently, we found that these exosomes express...

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Detalles Bibliográficos
Autores principales: Su, Qiang, Lv, Xiang-Wei, Xu, Yu-Li, Cai, Ru-Ping, Dai, Ri-Xin, Yang, Xi-Heng, Zhao, Wei-Kun, Kong, Bing-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920812/
https://www.ncbi.nlm.nih.gov/pubmed/33717651
http://dx.doi.org/10.1016/j.omtn.2021.02.005