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SIRT1-induced deacetylation of Akt expedites platelet phagocytosis and delays HEMEC aging

Maintaining the health of the endothelium is of critical importance to prevention against cell aging. The current study was performed to clarify the role of sirtuin1 (SIRT1) in platelet phagocytosis in cell aging and identified its downstream molecular mechanism. Platelet phagocytosis by human endom...

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Detalles Bibliográficos
Autores principales: Lan, Yong, Dong, Min, Li, Yongjun, Diao, Yongpeng, Chen, Zuoguang, Li, Yangfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920857/
https://www.ncbi.nlm.nih.gov/pubmed/33717652
http://dx.doi.org/10.1016/j.omtn.2021.01.023