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Clinical Significance of Receptor-Interacting Protein 3 and Parkin, Essential Molecules for Necroptosis, in Breast Cancer

PURPOSE: Receptor-interacting protein 3 (RIP3) is the main initiator of necroptosis. Parkin prevents the formation of the RIP1–RIP3 complex by promoting polyubiquitination of RIP3. However, the mechanism by which necroptosis affects the clinical features of breast cancer and prognosis is not known....

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Detalles Bibliográficos
Autores principales: Won, Kyu Yeoun, Min, Sun Young, Song, Jeong-Yoon, Lim, Sung-Jig, Han, Sang-Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Breast Cancer Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920860/
https://www.ncbi.nlm.nih.gov/pubmed/33634619
http://dx.doi.org/10.4048/jbc.2021.24.e12