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T Cells Actively Infiltrate the White Matter of the Aging Monkey Brain in Relation to Increased Microglial Reactivity and Cognitive Decline

Normal aging is characterized by declines in processing speed, learning, memory, and executive function even in the absence of neurodegenerative diseases such as Alzheimer's Disease (AD). In normal aging monkeys and humans, neuronal loss does not account for cognitive impairment. Instead, loss...

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Detalles Bibliográficos
Autores principales: Batterman, Katelyn V., Cabrera, Payton E., Moore, Tara L., Rosene, Douglas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920950/
https://www.ncbi.nlm.nih.gov/pubmed/33664743
http://dx.doi.org/10.3389/fimmu.2021.607691