From thiol-subtilisin to omniligase: Design and structure of a broadly applicable peptide ligase

Omniligase-1 is a broadly applicable enzyme for peptide bond formation between an activated acyl donor peptide and a non-protected acyl acceptor peptide. The enzyme is derived from an earlier subtilisin variant called peptiligase by several rounds of protein engineering aimed at increasing synthetic...

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Detalles Bibliográficos
Autores principales: Toplak, Ana, Teixeira de Oliveira, Eduardo F., Schmidt, Marcel, Rozeboom, Henriëtte J., Wijma, Hein J., Meekels, Linda K.M., de Visser, Rowin, Janssen, Dick B., Nuijens, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921005/
https://www.ncbi.nlm.nih.gov/pubmed/33717424
http://dx.doi.org/10.1016/j.csbj.2021.02.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921005/
https://www.ncbi.nlm.nih.gov/pubmed/33717424
http://dx.doi.org/10.1016/j.csbj.2021.02.002

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