From thiol-subtilisin to omniligase: Design and structure of a broadly applicable peptide ligase

Omniligase-1 is a broadly applicable enzyme for peptide bond formation between an activated acyl donor peptide and a non-protected acyl acceptor peptide. The enzyme is derived from an earlier subtilisin variant called peptiligase by several rounds of protein engineering aimed at increasing synthetic...

Descripción completa

Detalles Bibliográficos
Autores principales: Toplak, Ana, Teixeira de Oliveira, Eduardo F., Schmidt, Marcel, Rozeboom, Henriëtte J., Wijma, Hein J., Meekels, Linda K.M., de Visser, Rowin, Janssen, Dick B., Nuijens, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921005/
https://www.ncbi.nlm.nih.gov/pubmed/33717424
http://dx.doi.org/10.1016/j.csbj.2021.02.002

Ejemplares similares

Ejemplares similares