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First-in-human imaging and kinetic analysis of vesicular acetylcholine transporter density in the heart using [(18)F]FEOBV PET

In contrast to cardiac sympathetic activity which can be assessed with established PET tracers, there are currently no suitable radioligands to measure cardiac parasympathetic (cholinergic) activity. A radioligand able to measure cardiac cholinergic activity would be an invaluable clinical and resea...

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Detalles Bibliográficos
Autores principales: Saint-Georges, Zacharie, Zayed, Vanessa K., Dinelle, Katie, Cassidy, Clifford, Soucy, Jean-Paul, Massarweh, Gassan, Rotstein, Benjamin, Nery, Pablo B., Guimond, Synthia, deKemp, Robert, Tuominen, Lauri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921026/
https://www.ncbi.nlm.nih.gov/pubmed/32909238
http://dx.doi.org/10.1007/s12350-020-02323-w