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BMP6/TAZ-Hippo signaling modulates angiogenesis and endothelial cell response to VEGF

The BMP/TGFβ-Smad, Notch and VEGF signaling guides formation of endothelial tip and stalk cells. However, the crosstalk of bone morphogenetic proteins (BMPs) and vascular endothelial growth factor receptor 2 (VEGFR2) signaling has remained largely unknown. We demonstrate that BMP family members regu...

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Detalles Bibliográficos
Autores principales: Pulkkinen, H. H., Kiema, M., Lappalainen, J. P., Toropainen, A., Beter, M., Tirronen, A., Holappa, L., Niskanen, H., Kaikkonen, M. U., Ylä-Herttuala, S., Laakkonen, Johanna P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921060/
https://www.ncbi.nlm.nih.gov/pubmed/33021694
http://dx.doi.org/10.1007/s10456-020-09748-4