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BMP6/TAZ-Hippo signaling modulates angiogenesis and endothelial cell response to VEGF
The BMP/TGFβ-Smad, Notch and VEGF signaling guides formation of endothelial tip and stalk cells. However, the crosstalk of bone morphogenetic proteins (BMPs) and vascular endothelial growth factor receptor 2 (VEGFR2) signaling has remained largely unknown. We demonstrate that BMP family members regu...
Autores principales: | Pulkkinen, H. H., Kiema, M., Lappalainen, J. P., Toropainen, A., Beter, M., Tirronen, A., Holappa, L., Niskanen, H., Kaikkonen, M. U., Ylä-Herttuala, S., Laakkonen, Johanna P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921060/ https://www.ncbi.nlm.nih.gov/pubmed/33021694 http://dx.doi.org/10.1007/s10456-020-09748-4 |
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