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Mechanical stretch promotes hypertrophic scar formation through mechanically activated cation channel Piezo1

Hypertrophic scar (HS) formation is a skin fibroproliferative disease that occurs following a cutaneous injury, leading to functional and cosmetic impairment. To date, few therapeutic treatments exhibit satisfactory outcomes. The mechanical force has been shown to be a key regulator of HS formation,...

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Detalles Bibliográficos
Autores principales: He, Jiahao, Fang, Bin, Shan, Shengzhou, Xie, Yun, Wang, Chuandong, Zhang, Yifan, Zhang, Xiaoling, Li, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921104/
https://www.ncbi.nlm.nih.gov/pubmed/33649312
http://dx.doi.org/10.1038/s41419-021-03481-6