Cholesterol loading suppresses the atheroinflammatory gene polarization of human macrophages induced by colony stimulating factors

In atherosclerotic lesions, blood-derived monocytes differentiate into distinct macrophage subpopulations, and further into cholesterol-filled foam cells under a complex milieu of cytokines, which also contains macrophage-colony stimulating factor (M-CSF) and granulocyte–macrophage-colony stimulatin...

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Detalles Bibliográficos
Autores principales: Lappalainen, Jani, Yeung, Nicolas, Nguyen, Su D., Jauhiainen, Matti, Kovanen, Petri T., Lee-Rueckert, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921113/
https://www.ncbi.nlm.nih.gov/pubmed/33649397
http://dx.doi.org/10.1038/s41598-021-84249-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921113/
https://www.ncbi.nlm.nih.gov/pubmed/33649397
http://dx.doi.org/10.1038/s41598-021-84249-y

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