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Genome-Wide Analysis of Differentially Expressed miRNAs and Their Associated Regulatory Networks in Lenses Deficient for the Congenital Cataract-Linked Tudor Domain Containing Protein TDRD7

Mutations/deficiency of TDRD7, encoding a tudor domain protein involved in post-transcriptional gene expression control, causes early onset cataract in humans. While Tdrd7 is implicated in the control of key lens mRNAs, the impact of Tdrd7 deficiency on microRNAs (miRNAs) and how this contributes to...

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Detalles Bibliográficos
Autores principales: Anand, Deepti, Al Saai, Salma, Shrestha, Sanjaya K., Barnum, Carrie E., Chuma, Shinichiro, Lachke, Salil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921330/
https://www.ncbi.nlm.nih.gov/pubmed/33665188
http://dx.doi.org/10.3389/fcell.2021.615761