Structure of mammalian Mediator complex reveals Tail module architecture and interaction with a conserved core

The Mediator complex plays an essential and multi-faceted role in regulation of RNA polymerase II transcription in all eukaryotes. Structural analysis of yeast Mediator has provided an understanding of the conserved core of the complex and its interaction with RNA polymerase II but failed to reveal...

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Detalles Bibliográficos
Autores principales: Zhao, Haiyan, Young, Natalie, Kalchschmidt, Jens, Lieberman, Jenna, El Khattabi, Laila, Casellas, Rafael, Asturias, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921410/
https://www.ncbi.nlm.nih.gov/pubmed/33649303
http://dx.doi.org/10.1038/s41467-021-21601-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921410/
https://www.ncbi.nlm.nih.gov/pubmed/33649303
http://dx.doi.org/10.1038/s41467-021-21601-w

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