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Structure of mammalian Mediator complex reveals Tail module architecture and interaction with a conserved core
The Mediator complex plays an essential and multi-faceted role in regulation of RNA polymerase II transcription in all eukaryotes. Structural analysis of yeast Mediator has provided an understanding of the conserved core of the complex and its interaction with RNA polymerase II but failed to reveal...
Autores principales: | Zhao, Haiyan, Young, Natalie, Kalchschmidt, Jens, Lieberman, Jenna, El Khattabi, Laila, Casellas, Rafael, Asturias, Francisco J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921410/ https://www.ncbi.nlm.nih.gov/pubmed/33649303 http://dx.doi.org/10.1038/s41467-021-21601-w |
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