TGFβ/cyclin D1/Smad-mediated inhibition of BMP4 promotes breast cancer stem cell self-renewal activity

Basal-like triple-negative breast cancers (TNBCs) display poor prognosis, have a high risk of tumor recurrence, and exhibit high resistance to drug treatments. The TNBC aggressive features are largely due to the high proportion of cancer stem cells present within these tumors. In this study, we inve...

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Detalles Bibliográficos
Autores principales: Yan, Gang, Dai, Meiou, Zhang, Chenjing, Poulet, Sophie, Moamer, Alaa, Wang, Ni, Boudreault, Julien, Ali, Suhad, Lebrun, Jean-Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921419/
https://www.ncbi.nlm.nih.gov/pubmed/33649296
http://dx.doi.org/10.1038/s41389-021-00310-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921419/
https://www.ncbi.nlm.nih.gov/pubmed/33649296
http://dx.doi.org/10.1038/s41389-021-00310-5

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