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Cells recognize osmotic stress through liquid–liquid phase separation lubricated with poly(ADP-ribose)

Cells are under threat of osmotic perturbation; cell volume maintenance is critical in cerebral edema, inflammation and aging, in which prominent changes in intracellular or extracellular osmolality emerge. After osmotic stress-enforced cell swelling or shrinkage, the cells regulate intracellular os...

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Detalles Bibliográficos
Autores principales: Watanabe, Kengo, Morishita, Kazuhiro, Zhou, Xiangyu, Shiizaki, Shigeru, Uchiyama, Yasuo, Koike, Masato, Naguro, Isao, Ichijo, Hidenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921423/
https://www.ncbi.nlm.nih.gov/pubmed/33649309
http://dx.doi.org/10.1038/s41467-021-21614-5