The role of Schlafen 11 (SLFN11) as a predictive biomarker for targeting the DNA damage response

The therapeutic landscape of drugs targeting the DNA damage response (DDR) is rapidly expanding; however, an urgent unmet need remains for validated predictive biomarkers of response. SLFN11 has emerged as a promising predictor of sensitivity to DNA-damaging chemotherapies, and recently, been associ...

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Detalles Bibliográficos
Autores principales: Coleman, Niamh, Zhang, Bingnan, Byers, Lauren A., Yap, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921443/
https://www.ncbi.nlm.nih.gov/pubmed/33328609
http://dx.doi.org/10.1038/s41416-020-01202-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921443/
https://www.ncbi.nlm.nih.gov/pubmed/33328609
http://dx.doi.org/10.1038/s41416-020-01202-y

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