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The role of Schlafen 11 (SLFN11) as a predictive biomarker for targeting the DNA damage response
The therapeutic landscape of drugs targeting the DNA damage response (DDR) is rapidly expanding; however, an urgent unmet need remains for validated predictive biomarkers of response. SLFN11 has emerged as a promising predictor of sensitivity to DNA-damaging chemotherapies, and recently, been associ...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921443/ https://www.ncbi.nlm.nih.gov/pubmed/33328609 http://dx.doi.org/10.1038/s41416-020-01202-y |