Local hyperactivation of L-type Ca(2+) channels increases spontaneous Ca(2+) release activity and cellular hypertrophy in right ventricular myocytes from heart failure rats

Right ventricle (RV) dysfunction is an independent predictor of patient survival in heart failure (HF). However, the mechanisms of RV progression towards failing are not well understood. We studied cellular mechanisms of RV remodelling in a rat model of left ventricle myocardial infarction (MI)-caus...

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Detalles Bibliográficos
Autores principales: Medvedev, Roman Y., Sanchez-Alonso, Jose L., Mansfield, Catherine A., Judina, Aleksandra, Francis, Alice J., Pagiatakis, Christina, Trayanova, Natalia, Glukhov, Alexey V., Miragoli, Michele, Faggian, Giuseppe, Gorelik, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921450/
https://www.ncbi.nlm.nih.gov/pubmed/33649357
http://dx.doi.org/10.1038/s41598-021-84275-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921450/
https://www.ncbi.nlm.nih.gov/pubmed/33649357
http://dx.doi.org/10.1038/s41598-021-84275-w

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