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Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis

Exon junction complexes (EJCs) mark untranslated spliced mRNAs and are crucial for the mRNA lifecycle. An imbalance in EJC dosage alters mouse neural stem cell (mNSC) division and is linked to human neurodevelopmental disorders. In quiescent mNSC and immortalized human retinal pigment epithelial (RP...

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Detalles Bibliográficos
Autores principales: Kwon, Oh Sung, Mishra, Rahul, Safieddine, Adham, Coleno, Emeline, Alasseur, Quentin, Faucourt, Marion, Barbosa, Isabelle, Bertrand, Edouard, Spassky, Nathalie, Le Hir, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921557/
https://www.ncbi.nlm.nih.gov/pubmed/33649372
http://dx.doi.org/10.1038/s41467-021-21590-w