Single-molecule fluorescence-based approach reveals novel mechanistic insights into human small heat shock protein chaperone function

Small heat shock proteins (sHsps) are a family of ubiquitous intracellular molecular chaperones; some sHsp family members are upregulated under stress conditions and play a vital role in protein homeostasis (proteostasis). It is commonly accepted that these chaperones work by trapping misfolded prot...

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Detalles Bibliográficos
Autores principales: Johnston, Caitlin L., Marzano, Nicholas R., Paudel, Bishnu P., Wright, George, Benesch, Justin L.P., van Oijen, Antoine M., Ecroyd, Heath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921601/
https://www.ncbi.nlm.nih.gov/pubmed/33288678
http://dx.doi.org/10.1074/jbc.RA120.015419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921601/
https://www.ncbi.nlm.nih.gov/pubmed/33288678
http://dx.doi.org/10.1074/jbc.RA120.015419

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