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Single-molecule fluorescence-based approach reveals novel mechanistic insights into human small heat shock protein chaperone function
Small heat shock proteins (sHsps) are a family of ubiquitous intracellular molecular chaperones; some sHsp family members are upregulated under stress conditions and play a vital role in protein homeostasis (proteostasis). It is commonly accepted that these chaperones work by trapping misfolded prot...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921601/ https://www.ncbi.nlm.nih.gov/pubmed/33288678 http://dx.doi.org/10.1074/jbc.RA120.015419 |