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A robust platform for high-throughput screening of therapeutic strategies for acute and chronic spinal cord injury

Astrocytes and microglia are critical regulators of inflammatory cascade after spinal cord injury (SCI). Existing glial in vitro studies do not replicate inflammatory phases associated with SCI. Here, we report an in vitro model of mixed glial culture where inflammation is induced by the administrat...

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Detalles Bibliográficos
Autores principales: Patil, Vaibhav, O'Connell, Enda, Quinlan, Leo R., Fearnhead, Howard, McMahon, Siobhan, Pandit, Abhay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921603/
https://www.ncbi.nlm.nih.gov/pubmed/33718834
http://dx.doi.org/10.1016/j.isci.2021.102182