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An optimized protocol for rapid, sensitive and robust on-bead ChIP-seq from primary cells
Integrative analysis of next-generation sequencing data can help understand disease mechanisms. Specifically, ChIP-seq can illuminate where transcription regulators bind to regulate transcription. A major obstacle to performing this assay on primary cells is the low numbers obtained from tissues. Th...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921621/ https://www.ncbi.nlm.nih.gov/pubmed/33718886 http://dx.doi.org/10.1016/j.xpro.2021.100358 |