S-Trimer, a COVID-19 subunit vaccine candidate, induces protective immunity in nonhuman primates

SARS-CoV-2 is the underlying cause for the COVID-19 pandemic. Like most enveloped RNA viruses, SARS-CoV-2 uses a homotrimeric surface antigen to gain entry into host cells. Here we describe S-Trimer, a native-like trimeric subunit vaccine candidate for COVID-19 based on Trimer-Tag technology. Immuni...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Joshua G., Su, Danmei, Song, Tian-Zhang, Zeng, Yilan, Huang, Weijin, Wu, Jinhua, Xu, Rong, Luo, Peiwen, Yang, Xiaofang, Zhang, Xiaodong, Luo, Shuangru, Liang, Ying, Li, Xinglin, Huang, Jiaju, Wang, Qiang, Huang, Xueqin, Xu, Qingsong, Luo, Mei, Huang, Anliang, Luo, Dongxia, Zhao, Chenyan, Yang, Fan, Han, Jian-Bao, Zheng, Yong-Tang, Liang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921634/
https://www.ncbi.nlm.nih.gov/pubmed/33649323
http://dx.doi.org/10.1038/s41467-021-21634-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921634/
https://www.ncbi.nlm.nih.gov/pubmed/33649323
http://dx.doi.org/10.1038/s41467-021-21634-1

Ejemplares similares