Cargando…

PKA-RIIβ autophosphorylation modulates PKA activity and seizure phenotypes in mice

Temporal lobe epilepsy (TLE) is one of the most common and intractable neurological disorders in adults. Dysfunctional PKA signaling is causally linked to the TLE. However, the mechanism underlying PKA involves in epileptogenesis is still poorly understood. In the present study, we found the autopho...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jingliang, Zhang, Chenyu, Chen, Xiaoling, Wang, Bingwei, Ma, Weining, Yang, Yang, Zheng, Ruimao, Huang, Zhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921646/
https://www.ncbi.nlm.nih.gov/pubmed/33649504
http://dx.doi.org/10.1038/s42003-021-01748-4