The contribution of PARP1, PARP2 and poly(ADP-ribosyl)ation to base excision repair in the nucleosomal context

The regulation of repair processes including base excision repair (BER) in the presence of DNA damage is implemented by a cellular signal: poly(ADP-ribosyl)ation (PARylation), which is catalysed by PARP1 and PARP2. Despite ample studies, it is far from clear how BER is regulated by PARPs and how the...

Descripción completa

Detalles Bibliográficos
Autores principales: Kutuzov, M. M., Belousova, E. A., Kurgina, T. A., Ukraintsev, A. A., Vasil’eva, I. A., Khodyreva, S. N., Lavrik, O. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921663/
https://www.ncbi.nlm.nih.gov/pubmed/33649352
http://dx.doi.org/10.1038/s41598-021-84351-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921663/
https://www.ncbi.nlm.nih.gov/pubmed/33649352
http://dx.doi.org/10.1038/s41598-021-84351-1

Ejemplares similares