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PEGylated Serp-1 Markedly Reduces Pristane-Induced Experimental Diffuse Alveolar Hemorrhage, Altering uPAR Distribution, and Macrophage Invasion

Diffuse alveolar hemorrhage (DAH) is one of the most serious clinical complications of systemic lupus erythematosus (SLE). The prevalence of DAH is reported to range from 1 to 5%, but while DAH is considered a rare complication there is a reported 50–80% mortality. There is at present no proven effe...

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Detalles Bibliográficos
Autores principales: Guo, Qiuyun, Yaron, Jordan R., Wallen, John W., Browder, Kyle F., Boyd, Ryan, Olson, Tien L., Burgin, Michelle, Ulrich, Peaches, Aliskevich, Emily, Schutz, Lauren N., Fromme, Petra, Zhang, Liqiang, Lucas, Alexandra R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921738/
https://www.ncbi.nlm.nih.gov/pubmed/33665212
http://dx.doi.org/10.3389/fcvm.2021.633212