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Pharmacologic Targeting of BET Proteins Attenuates Hyperuricemic Nephropathy in Rats

Hyperuricemia is an independent risk factor for renal damage and promotes the progression of chronic kidney disease. In this study, we investigated the effect of I-BET151, a small-molecule inhibitor targeting the bromodomain and extraterminal (BET) proteins, on the development of hyperuricemic nephr...

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Detalles Bibliográficos
Autores principales:	Xiong, Chongxiang, Deng, Jin, Wang, Xin, Shao, Xiaofei, Zhou, Qin, Zou, Hequn, Zhuang, Shougang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921804/ https://www.ncbi.nlm.nih.gov/pubmed/33664670 http://dx.doi.org/10.3389/fphar.2021.636154

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